Relationship between immune cells and cytokines
Levels of sCD40L showed a significant correlation (R2value= 0.32, p= 0.04) with proportions of pre-switched B cells. Increasing proportions of pre-switched B cells were accompanied with decreasing amounts of sCD40L in IgAN, but not in HC (Fig. 7). Levels of IL-6 showed a significant relationship (R2 value= 0.39, p= 0.03) with proportions of plasmablasts. However, there was no significant correlation between levels of MCP-1 and non-classical monocytes (R2 value= 0.07, p = 0.37) (Fig. 7) or IL-6 levels and non-classical monocytes (data not shown).