GDM and children allergen sensitization
One study was included in subgroup analysis, with a pooled effect
estimate of 1.45 (95%CI:0.40, 5.23). In this study, the sensitization
outcomes included food sensitization, aeroallergen sensitization and
total sensitization (22). Allergen sensitization was defined as specific
IgE>0.10 kUA/L resulting from at least one of the tested
allergens, including food (egg white, milk, peanut, soy, shrimp, wheat,
and walnut) and aeroallergens (dermatophygoides pteronyssinus and
dermatophygoides farinae, German cockroach, cat, dog, and Alternaria
alternata). Similar criterion was used in other studies (23, 24). Due to
the heterogeneity of the studies (I2 =70.5%,
P=0.005), a random effect model was used to show the relationship
between gestational diabetes and sensitization. (Figure 3(d) )