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Highlight. Total-serum IgE and FcεRI expression on basophils were higher in AD patients than in HCs, although surface-bound IgE on basophils was equivalent.
Baseline CD203c/CD63 was spontaneously upregulated in AD patients, but responsiveness to anti-IgE stimulation was lower in AD patients than in HCs.
Responsiveness to anti-FcεRI stimulation was higher than that to anti-IgE stimulation in AD patients, contrary to HCs.
→, normal expression; ↑, mildly increased expression; ↑↑, moderately increased response ratio; ↑↑↑, severely increased response ratio; ↑↑↑↑, extremely increased response ratio.