Conclusions
Our study is important in that it not only shows that eSET in
freeze-only cycles maintains similar PRs to those of DET after the first
transfer but also that a second consecutive SET brings the best
cost-benefit ratio, as it increases the success rates compared with DET
and decreases the possibility multiple pregnancies. Considering the
existence of variables that are not subject to control in a clinical
routine, and those inherent to the procedure that can be corrected in a
subsequent cycle, it is reasonable to perceive that the transfer of
embryos in separate events (consecutive SETs) will allow possible
corrections and produce a higher success rate than the transfer of two
embryos in a single event. Finally, the freeze-only strategy with
consecutive SETs is a feasible and efficient approach leading to an
increased chance of implantation and avoidance of multiple gestations.