Conclusions

Our study is important in that it not only shows that eSET in freeze-only cycles maintains similar PRs to those of DET after the first transfer but also that a second consecutive SET brings the best cost-benefit ratio, as it increases the success rates compared with DET and decreases the possibility multiple pregnancies. Considering the existence of variables that are not subject to control in a clinical routine, and those inherent to the procedure that can be corrected in a subsequent cycle, it is reasonable to perceive that the transfer of embryos in separate events (consecutive SETs) will allow possible corrections and produce a higher success rate than the transfer of two embryos in a single event. Finally, the freeze-only strategy with consecutive SETs is a feasible and efficient approach leading to an increased chance of implantation and avoidance of multiple gestations.