2.6 Severe disease criteria
Patients from any group presented with any one of the following were
categorized to have a severe disease:
- Oxygen requirement of more than 10 liters for 90% saturation.
- 50% of lung involvement on either chest X-ray or HRCT.
- Multi-organ dysfunction
- CRP > 10 mg/L, D-dimer > 1000 mg/mL, serum
ferritin > 1000 ng/mL.
- Secondary infection (diagnosed by blood culture and sensitivity test
or raised procalcitonin).
- Shock or use of inotropes.
- [PaO2/FiO2] (PF ratio) < 118 mmHg.