Figures
Figure 1. Clinical timeline for Case R. ERCP: endoscopic
retrograde cholangiopancreatography; RT-PCR: Reverse-transcription
polymerase chain reaction; S: serum sample; NP nasopharyngeal sample;
(+) Positive result; (-) Negative result; RBC: red blood cells
transfusion. CT: computerized axial tomography scan. MO failure:
multiorgan failure; HFNC: high-flow nasal cannulas; O. intubation:
orotracheal intubation
Figure 2. Network of relationships obtained from whole genome
sequencing analysis for the outbreak strains. Each dot corresponds to a
single nucleotide polymorphism. When two or more cases share identical
genome (zero single nucleotide polymorphisms between them) they are
included in the same box. mv: median vector: not sampled recent common
ancestor for the two branches. ANC: Wuhan-1 reference strain.
Figure 3. Distribution along the SARS-CoV-2 chromosome of the
single nucleotide polymorphisms identified in the two sequential
episodes of Case R. Each vertical black bar corresponds to a single
nucleotide polymorphism.