Figures
Figure 1. Clinical timeline for Case R. ERCP: endoscopic retrograde cholangiopancreatography; RT-PCR: Reverse-transcription polymerase chain reaction; S: serum sample; NP nasopharyngeal sample; (+) Positive result; (-) Negative result; RBC: red blood cells transfusion. CT: computerized axial tomography scan. MO failure: multiorgan failure; HFNC: high-flow nasal cannulas; O. intubation: orotracheal intubation
Figure 2. Network of relationships obtained from whole genome sequencing analysis for the outbreak strains. Each dot corresponds to a single nucleotide polymorphism. When two or more cases share identical genome (zero single nucleotide polymorphisms between them) they are included in the same box. mv: median vector: not sampled recent common ancestor for the two branches. ANC: Wuhan-1 reference strain.
Figure 3. Distribution along the SARS-CoV-2 chromosome of the single nucleotide polymorphisms identified in the two sequential episodes of Case R. Each vertical black bar corresponds to a single nucleotide polymorphism.