Study Selection
Eligibility criteria included original research studies, published in English, with COVID-19 patients (target population) that reported the effects of ACEIs/ARBs (intervention), in comparison with non ACEIs/ARBs use (comparison), on COVID-19 related outcomes. No restrictions were placed on the reported outcomes or study types. All records identified from the search strategy were exported from the databases and imported into Covidence® (31) whereby duplicate records were removed. Two reviewers (NA and LA) independently undertook titles and abstract screening for relevance, followed by selecting records for full-text screening and data extraction. At each stage, discrepancies were resolved through discussion until consensus was achieved. A third author (AK) verified the eligibility of the included studies.