Methods
This was a systematic review/meta-analysis conducted in Medline (OVID), Embase, Scopus, Cochrane library and medRxiv from inception to 22nd May-2020. English studies that evaluated the effect of ACEIs/ARBs among patients with COVID-19 were included. The study outcomes included any COVID-19 related-clinical outcomes. Studies’ quality was appraised using the Newcastle-Ottawa Scale. Data were analysed using the random-effects modelling stratified by ACEIs/ARBs, ACEIs, and ARBs. Heterogenicity was assessed using I2statistic. Several sub-group analyses were conducted to explore the impact of potential confounders.