Correlations of RAGE expression with patients’ survival rate
There was a total of 46 patients with MetPca. Of 46, 27 patients had RAGE positive on specimens, and 19 had a negative expression on specimens. When compared each other with respect to cancer recurrence, cancer-specific mortality, and follow-up period (month); recurrence rate (81,4% vs 78.9%, p=0.8), cancer-specific mortality (33.3% vs 26.3%, p=0.58) were statistically found to be non -significant. (See table 2, figure 2-3).
For the patients (total n=87) with localized prostate cancer, there were 47 patients with RAGE positive, 35 patients with RAGE negative. Five patients in the LPCa group had a positive surgical margin, so these patients were not included in the survival analysis. Comparison of these two groups patients, we did not find a significant difference for the cancer recurrence, duration of the follow-up, but we discovered that biochemical recurrence rate was found significantly higher in RAGE positive patients (p=0.00; table 2, figure 4).