RESULTS
Demographical and Biochemical and Immunohistochemical Parameters
Demographical, biochemical parameters and RAGE scores of three subgroups (BPH, LPCa, MetPCa) were demonstrated in table 1.
There were no significant RAGE expressions on the specimens of a total of 64 patients with BPH. RAGE expressions score of 24 diabetic and 40 non-diabetic patients with BPH were 0.5±0.65 (range 0-4) and 0.6±0.9 (range 0-4), respectively (diabetic vs.non-diabetic p>0.05). All biochemical parameters and RAGE scores of diabetic or non-diabetic patients with BPH were demonstrated in table 1.
There were 87 patients (diabetic 41; non-diabetic 46) with LPCa. RAGE scores of diabetic (n=41) and nondiabetic patients (n=46) with LPCa were found to be 4.7±3.1 (range 1-12) and 1.5±1.8 (range 0-9), respectively (diabetic vs. non-diabetic p=0.01). All biochemical parameters and RAGE scores of diabetic or nondiabetic patients with LPCa were demonstrated in table 1. There were 46 (diabetic 30, non-diabetic 16) patients with MetPCa. RAGE scores of diabetic (n=30) and nondiabetic patients (n=16) with MetPCa were found to be 4.9±3.6 (0-12) 1.6±1.5 (range 0-6), (diabetic vs.non-diabetic, p=0.00).
There was no difference between the patients’ group (BPH, LPCa, MetPCa) for the age, fasting plasma glucose, HbA1c, and diabetes duration (except for diabetic patients).