References
  1. Guan WJ, Ni ZY, Hu Y, Liang WH, OU CQ, HE JX, LIU L, SHAN H, LEI CL, HUI DSC, DU B, LI LJ, ZENG G, YUEN KY, CHEN R.C, TANG CL, WANG T, CHEN PY, XIANG J., LI S. Y., WANG J. L., LIANG Z. J., PENG Y. X., WEI L., LIU Y., HU Y. H., PENG P., WANG J. M., LIU J. Y., CHEN Z., LI G., ZHENG Z. J., QIU S. Q., LUO J., YE C. J., ZHU S. Y., ZHONG N. S. & CHINA MEDICAL TREATMENT EXPERT GROUP FOR C. 2020. China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020; NEJMoa2002032. https://doi.org/10.1056/ NEJMoa2002032
  2. Dong Y, Mo X, Hu Y, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Pediatrics 2020; published online March 16. DOI:10.1542/peds.2020-0702
  3. https://www.care.gov.eg/EgyptCare/Index.aspx (accessed on 17/6/2020))
  4. Cai J, Xu J, Lin D, Yang Z, Xu L, Qu Z, Zhang Y, Zhang H, Jia R, Liu P, Wang X, Ge Y, Xia A, Tian H, Chang H, Wang C, Li J, Wang J, and Zeng M. A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features Clin Infect Dis. 2020 Feb 28 : ciaa198. doi: 10.1093/cid/ciaa198
  5. Dong Y, Mo X, Hu Y, Xin Qi, Fan Jiang, Zhongyi Jiang and Shilu Tong. Epidemiology of COVID-19 Among Children in China. Pediatrics. 2020 Mar. DOI: 10.1542/peds.2020-0702.
  6. Ogimi C, Englund JA, Bradford MC, Qin X, Boeckh M, Waghmare A. Characteristics and outcomes of coronavirus infection in children: the role of viral factors and an immunocompromised state. J Pediatric Infect Dis Soc. 2019;8(1):21-28.
  7. Xia Y, Jin R, Zhao J, Li W, Shen H. Risk of COVID-19 for cancer patients. Lancet Oncol 2020; published online March 3. https:// doi:10·1016/S1470–2045(20)30150–9)
  8. Wang H, Zhang L. Risk of COVID-19 for patients with cancer. Lancet Oncol 2020; published online March 3. https://doi. org/10•1016/S1470–2045(20)30149–2
  9. Kotecha SR. Challenges posed by COVID-19 to children with cancer. The lancet oncology 2020; 21(5):e235
  10. WHO. WHO director-general’s statement on IHR Emergency Committee on Novel Coronavirus (2019-nCoV). Available at: https://www.who.int/dg/speeches/detail/who-director-general-s-statement-on-ihr-emergency-committee-on-novel-coronavirus-(2019-ncov). Accessed March 3, 2020
  11. Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 infection in children. N Engl J Med. 2020;382:1663-1665.
  12. Minotti C, Tirelli F, Barbieri E, Giaquinto C, Donà D. How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. J Infect . 2020;81(1):e61-e66.
  13. Sieni E, Pegoraro F, Casini T, et al. Favourable outcome of coronavirus disease 2019 in a 1-year-old girl with acute myeloid leukaemia and severe treatment-induced immunosuppression. Br J Haematol . 2020;189(6):e222-e224. doi:10.1111/bjh.16781
  14. Abdulamir AS, Hafidh RR. The Possible Immunological Pathways for the Variable Immunopathogenesis of COVID—19 Infections among Healthy Adults, Elderly and Children. Electron J Gen Med. 2020;17(4).
  15. Ding YY, Ramakrishna S, Long AH, et al. Delayed cancer diagnoses and high mortality in children during the COVID-19 pandemic [published online ahead of print, 2020 Jun 26]. Pediatr Blood Cancer . 2020;e28427. doi:10.1002/pbc.28427
  16. Madariaga A, McMullen M, Sheikh S, et al. COVID-19 testing in cancer patients: Does one size fit all? [published online ahead of print, 2020 Jul 2]. Clin Cancer Res . 2020; clincanres.2224.2020.
  17. Bose S, Adapa S, Aeddula NR, et al. Medical Management of COVID-19: Evidence and Experience. J Clin Med Res . 2020;12(6):329-343.
  18. Athale U, Moghrabi A, Nayiager T, Delva YL, Thabane L, Chan AK. von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: an impact of peripheral blasts. Pediatr Blood Cancer . 2010;54(7):963-969.
  19. Middleton EA, He XY, Denorme F, et al. Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome [published online ahead of print, 2020 Jun 29]. Blood . 2020;blood.2020007008. doi:10.1182/blood.2020007008
  20. Schorling RM, Pfrepper C, Golombek T, et al. Evaluation of Biomarkers for the Prediction of Venous Thromboembolism in Ambulatory Cancer Patients [published online ahead of print, 2020 Jun 24]. Oncol Res Treat. 2020;1-10.
  21. Aryal MR, Gosain R, Donato A, et al. Venous Thromboembolism in COVID-19: Towards an Ideal Approach to Thromboprophylaxis, Screening, and Treatment. Curr Cardiol Rep . 2020;22(7):52.
  22. Feng X, Li S, Sun Q, et al. Immune-Inflammatory Parameters in COVID-19 Cases: A Systematic Review and Meta-Analysis. Front Med (Lausanne) . 2020; 7:301.
  23. Chen ZM, Fu JF, Shu Q, Chen YH, Hua CZ, Li FB, et al. Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus. World J Pediatr. 2020.
Figure Legend