IDX promotes T cells cytolytic potential following degranulation upon coculture with NPC tumor cells
(A) Flow cytometry plots of PBMCs alone and in coculture following IDX stimulation for 3 days. Gated frequencies represent the percentage of CD4+ or CD8+ T cells among Ki67, granzyme B and CD107a bright events. Bar chart of Ki67 (B), granzyme B (C) and CD107a (D) expression in CD8+ T corresponding to the above flow cytometry plots. Statistical significance was analyzed using 2-way ANOVA, *p < 0.05; **p < 0.005 when compared with control (DMSO) in PBMCs cultured alone; #p < 0.05; ## p < 0.005 when compared with control (DMSO) in cocultures.