Data sources
A Beaumont Health registry was established to calculate all
demographics, clinical characteristics, comorbid conditions, pertinent
medications, and outcomes of patients who underwent left atrial ablation
procedures. The data from the registry was abstracted through automated
reports generated through a multi-platform database query tool from
Beaumont Health’s electronic medical record. Demographics abstracted
from the registry for the purpose of this study were age, sex, race, and
weight. Comorbid conditions abstracted were hypertension, diabetes
mellitus, coronary artery disease, peripheral artery disease, stroke/TIA
history, and congestive heart failure. Laboratory values abstracted were
the peri-procedural race based GFR. The peri-procedural medication
administration record for each patient was abstracted from the registry
and compared with the antiplatelet medications aspirin, clopidogrel,
ticagrelor, prasugrel, and dipyridamole. During the pre-procedure
history and physical, the duration of held oral anticoagulant doses was
documented and collected in the registry.
Data review and collected was performed by a physician trained to
abstract the needed data into SharePoint. Heparin doses and
administration times were obtained by the medical record by review of
the anesthesia procedure log. ACT values and result times were
documented by the electrophysiology laboratory staff, and reviewed in
the medical record. Left ventricular ejection fraction was abstracted
from the electronic medical record after review of the most recent
echocardiogram. All occurrences of major bleeding or thrombotic events
were reviewed and adjudicated by a Board Certified Cardiologist.