FIGURE LEGEND
Figure 1 - Demonstrated are the ACT outcomes comparing the usual care, to the protocol guided cohort. Aggregate data includes all patients regardless of pre-procedure oral anticoagulant. Those on pre-procedure DOAC, warfarin, and no oral anticoagulant (None) are also shown. Panel A shows the proportion (%) of ACT > 300 seconds on first draw after the heparin bolus was administered. Panel B shows the proportion (%) of ACT >400 seconds on first draw after the heparin bolus was administered. Panel C shows the total proportion (%) of ACT values > 300 seconds during the procedure. Panel D shows the total proportion (%) of ACT values >400 seconds during the procedure.
Figure 2 - Demonstrated are the time outcomes to achieved an ACT > 300 seconds, comparing the usual care, to the protocol guided cohort. Aggregate data includes all patients regardless of pre-procedure oral anticoagulant. Those on pre-procedure DOAC, warfarin, and no oral anticoagulant (None) are also shown. Error bars indicate standard error. Panel A shows the time to an ACT> 300 seconds when measured after Heparin bolus administered. Panel B shows the time to an ACT > 300 seconds when measured after the transseptal puncture was performed.
Figure 3 - Demonstrated are average weight-based bolus (units/Kg), comparing the usual care, to the protocol guided cohort. Aggregate data includes all patients regardless of pre-procedure oral anticoagulant. Those on pre-procedure DOAC, warfarin, and no oral anticoagulant (None) are also shown. Error bars indicate standard error.
Figure 4 – Data from all patients receiving no pre-procedure oral anticoagulant are presented, regardless of cohort designation. The weight-based heparin bolus administered is plotted against the first ACT value after heparin administration. Blue line represents linear regression (p=0.011), with a goodness of fit R2 value of 0.297.