2.2 Psoriasis severity evaluation
To evaluate the severity of inflammation in the ears and neck skin of
mice, we used an objective scoring system based on the clinical
Psoriasis area and severity index (PASI). Erythema, scaling, and
thickening were scored independently on a scale of 0 to 4: 0, none; 1,
slight; 2, moderate; 3, marked; or 4, very marked (van der Fits et al.,
2009).