Conclusion:
- This case emphasizes that with the availability of novel agents
(Daratumumab) and use of bortezomib, even refractory PBL could be
treated successfully.
- This case signifies that daEPOCH followed by upfront autologous stem
cell transplant in CR1 is a suitable option in primary PBL giving
durable remission.
- To the best of our knowledge this is the first reported case of a
relapsed HIV negative PBL treated with AlloHCT who is disease-free for
more than 2 years.