NiCr metal matrix composite reinforced with Cr3C2 particles can be applied as coating to various pieces of equipment, including those operating under fatigue. In the present study, the nanometric powder was obtained by high energy milling and sprayed by the high velocity oxygen fuel technique on ASTM A516 steel substrate. The comparison was made between the layer obtained from powders in nanometric scale, micrometric scale and mixing 50% of both. The coating thickness, hardness, microstructure, porosity and roughness were evaluated. Fatigue tests were performed on the three coatings in addition to the layer free substrate. The effect of coating morphology and its roughness on fatigue performance was studied. The surface roughness of the Nano coating was significantly lower than both of the other coatings. However, the three different layers that were tested did not experience significant differences in their fatigue performance. All three coatings had lower fatigue performance than the steel substrate.