A total 822 pregnant women were involved into our research and 347 delivered in 2020 and the rest in 2019. The table 1 lists the comparison of two groups about mother characteristics. Maternal age (32.12±5.32vs31.01±4.21) and times of prenatal visits (10.49±2.15vs10.89±1.81) had the remarkable statistical significance(P<0.05). Score of PHQ-9 in 2019(4.96±1.38) was higher than it in 2020(1.46±2.09)(P<0.05). There was no conspicuous distinction in Gestational weight gain (GWG).