Definitions
Cardiac injury was defined if the serum level of high-sensitivity
troponin I (hs-cTnI) were above the 99th percentile upper reference
limit[2]. The illness severity of COVID-19 was
defined according to the Chinese management guideline for COVID-19
(version 7.0). Abnormalities on echocardiography defined as cardiac
chambers enlargement, cardiac dysfunction (defined as left ventricular
ejection fraction<50%), segment wall motion abnormality, left
ventricular wall thickening(>10mm) and/or pericardial
effusion. Right ventricular systolic function was represented by the
tricuspid anterior plane systolic excursion (TAPSE). Echocardiographic
signs of pulmonary hypertension includes the following:the peak
tricuspid regurgitation velocity is over 2.8m/s accompanied by the basal
diameter ratio of right ventricle/left ventricle >1.0;the
acceleration time of pulmonary artery is over 105msec and/or mild
systolic notching; the inferior cava diameter is more than 21mm with
decreased inspiratory collapse (<50 % in the condition of
sniffing or <20 % in quiet
inspiration)[3].