Abbreviations
IVM, ivermectin; MDA, mass drug administration; HLM, human liver microsomes; PHH, primary human hepatocyte; NADPH, reduced form of nicotinamide adenine dinucleotide phosphate; CYP450, cytochrome P450; UHPLC QTOF MS, ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry; HRMS, high resolution mass spectrometry; NMR, nuclear magnetic resonance; NTDs, neglected tropical diseases; HSQC, heteronuclear single quantum correlation; HMBC, heteronuclear multiple bond correlation