Statistical Analysis
Clinical characteristics, treatments, outcomes, and resource utilization between salicylate intoxication patients with and without AKI were compared using student’s t-test for continuous variables, and Chi-squared test for categorical variables. Clinical characteristics associated with AKI were identified using multivariable logistic regression with backward stepwise selection. The association of AKI with clinical outcomes was evaluated using logistic regression analysis, and the association of AKI with length of hospital stay and hospitalization cost was evaluated using linear regression analysis, with pre-specified adjustment for clinical characteristics. Statistical significance was achieved when two-tailed p-value <0.05. SPSS statistical software (version 22.0, IBM Corporation, Armonk, NY, USA) was used for all analyses.