Methods
An experimental rat model of allergic asthma was prepared using
ovalbumin. During the sensitization period, ovalbumin was inhaled alone
or in combination with rosuvastatin. Plethysmographic measurement of
pulmonary function was used to evaluate airway vagal activity; molecular
biological assay was used to examine the expression and activity of
medullary CD73 and the expression of eosinophil cationic protein 1
(ECP1) in the lungs.