Results
Of the total of 225 patients included in the study, 155 had BPH and 70 had PCa with pathology confirmation . The mean age of the patients was 66.54+ 8.19 years, and 67.8+ 6.85 years in Group 1 and Group 2, respectively. As seen in Table 1, the mean total PSA levels of the patients in Group 1 was 6.37+ 3.98 and Group 2 was 8.62+ 4.25. The total PSA, albumin, and lymphocyte differences between the groups were statistically significant (p=0.0002, p=0.0001, p= 0.005). The median value of the HALP scores in Group 1 and 2 were 49.43 and 51.2 respectively, and this was not statistically significant between two groups (p=0.737).
The HALP score had the least Area Under Curve (AUC) value compared to the others (0.514). Surprisingly, the AUC of Albumin was larger than PSA for diagnostic efficacy in PCa patients (0.696-0.656) (Figure 1), but this was not statistically significant (p=0.4580) (Table 2).
When comparing the different parameters with each other with the ROC analysis; the PSA levels were not statistically significant to hemoglobin, albumin level, lymphocyte, platelet count, or the HALP score. However, the albumin levels were statistically significant compared to the platelet count and HALP score (p=0.0033, p=0.0068), except PSA and lymphocyte (p=0.4580, p=0.1717) (Table 2).