objective clinical data
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at baseline and after 6 months - symptom control, frequency and severity
of exacerbations in the period since the last visit, lung function (FVC,
FEV1, MEF50), airway inflammation (FENO) measurement and medication use;
at baseline - skin prick (SPT) and total and specific IgE to inhaled
allergens, blood eosinophils and neutrophils, anthropometric measures
(height, weight, body mass index ) and for certain patients with
suggestive history for comorbidities -ENT examination, pH probing with
impedance for diagnostics of laryngopharyngeal reflux and
gastroesophageal reflux disease, polysomnography for diagnostics of
obstructive sleep apnoea syndrome, SPT and specific IgE to food and
insect venom allergens for diagnostics of food/insect venom
allergy
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