Virus and bateria
Virus
and bacteria data were obtained from nasopharyngeal swabs (NPS)
collected at enrolment. NPS were placed into skim milk tryptone glucose
glycerol broth (STGGB), stored at -80°C. NPS bacterial pathogens were
cultured at our institution22 and respiratory viruses
using PCR undertaken at the Queensland Paediatric Infectious Diseases
laboratory in Brisbane, as previously done19-21. For
this study, we combined any bacteria detected as a single variable and
only the two most frequently detected viruses (RSV and HRV) were
analysed (so as to allow inclusion of more data). Further methods are
detailed in the E-text file.