SE, standard error
Discussion
HD, as a common alternative treatment for ESRD patients, can prolong the
survival time of patients. Nevertheless, the high incidence of
cardiovascular disease, such as heart failure and coronary heart
disease, is the main cause of death. [7] Studies have shown the
relationship between increased LA size, volume, and major cardiovascular
events in ESRD [8]. There are many data available indicating that
the diastolic function of ESRD is damaged earlier than the change of LV
systolic function, and the change of LA function can more sensitively
reflect the change of diastolic function. [9] The LA function can
directly reflect the changes of atrioventricular pressure difference,
which is the direct embodiment of left atrial preload and afterload.
Thus, early detection of left atrial structural and functional
impairment is helpful for the selection of clinical treatment options in
the ESRD with preserved ejection fraction on HD. In the present study,
we demonstrated that LA dimension and volume increased in ESRD compared
to normal healthy groups, but the strain is lower. Additionally, the
strain parameters showed a better correlation with LV diastolic filling
pressure than conventional parameters.