2.1 Study Population
Every individual signed the informed consent forms approved by the
Ethics Committee of our hospital. Between August 2019 and April 2020, 37
patients with ESRD on regular HD aged 51.68±15.98 years participated in
this study and compared with 34 healthy control subjects, matched for
sex and body surface area (BSA).
Inclusion Criteria : We used the modified National Kidney
Foundation Classification of Chronic Kidney Disease, with ESRD defined
as estimated glomerular filtration
rate(eGFR)<15mL/min/1.73m2, and eGFR was
calculated by the MDRD formula. Adults≥18 years old and LVEF≥50%.Exclusion Criteria: Acute renal insufficiency, significant
valvular heart disease, arrhythmia, severe systemic diseases, low
ejection fraction (LVEF<50%) and poor echocardiographic
image.