2.1 Study Population
Every individual signed the informed consent forms approved by the Ethics Committee of our hospital. Between August 2019 and April 2020, 37 patients with ESRD on regular HD aged 51.68±15.98 years participated in this study and compared with 34 healthy control subjects, matched for sex and body surface area (BSA).
Inclusion Criteria : We used the modified National Kidney Foundation Classification of Chronic Kidney Disease, with ESRD defined as estimated glomerular filtration rate(eGFR)<15mL/min/1.73m2, and eGFR was calculated by the MDRD formula. Adults≥18 years old and LVEF≥50%.Exclusion Criteria: Acute renal insufficiency, significant valvular heart disease, arrhythmia, severe systemic diseases, low ejection fraction (LVEF<50%) and poor echocardiographic image.