2.1 Inclusion Criteria
In this evaluation, OG COSs that had developed or applied methodologies to determine which outcome areas or outcomes should be measured, or important in clinical trials or other forms of health research, were eligible for inclusion. We used the latest version whenever the COSs had been updated. Studies that; only reported the use of a COS, were systematic reviews of clinical trials, focused on systematic reviews and surveys of outcomes measured in clinical trials or quantitative descriptions (e.g. frequency) of outcomes, or protocol of COS, were excluded. There were no limitations on the year of publication, language, age of participants, and types of interventions.