Significance and Impact of the Study
To our knowledge, this is the first report which shows the genetic diversity of ESBL and mcr-1, and various virulent features of E. coli strains isolated from bovine clinical mastitis in three different provinces of China. The major carriers of the blaCTX-M-1 and blaCTX-M-9 were blaCTX-M-28 and blaCTX-M-14 alleles, respectively. The association of ESBL-producing E. coli with mcr-1 is of particular concern.
Keywords: Escherichia coli, Mastitis, Resistance, ESBL, mcr-1