The level of CD4+CCR6+CRTh2+memory Th2 cells is an effective index for the diagnosis of asthma in wheezing children.
There were significant differences in levels of serum IgE, level of CD4+CCR6+CRTh2+memory Th2 cells and age between children diagnosed with asthma and children with non-asthma outcomes. Binary logistic regression analysis and the Wald X2 test of each regression coefficient showed that the level of memory-type Th2 cells (OR, 29.926; 95% CI, 1.791-499.933; P=0.018) was independent risk factors for asthma in these children (Table 4). The ROC was adopted to calculate the sensitivity and specificity of the model. The area under the ROC curve was 0.922 (95%CI 0.836-1.000; P<0. 001.Figure 2).