The level of
CD4+CCR6+CRTh2+memory Th2 cells is an effective index for the diagnosis of asthma in
wheezing children.
There were significant differences in levels of serum IgE, level of
CD4+CCR6+CRTh2+memory Th2 cells and age between children diagnosed with asthma and
children with non-asthma outcomes.
Binary logistic regression
analysis and the Wald X2 test of each regression
coefficient showed that the level of memory-type Th2 cells (OR, 29.926;
95% CI, 1.791-499.933; P=0.018) was independent risk factors for asthma
in these children (Table 4). The ROC was adopted to calculate the
sensitivity and specificity of the model. The area under the ROC curve
was 0.922 (95%CI 0.836-1.000; P<0. 001.Figure 2).