Variable
Patients without 10% increase N=705 Patients with 10% increase N=473
P-Value
Age, years 58.5 (11.6) 58.0 (11.6) 0.5592
Male 558 (79.2) 331 (70.0) 0.0003
Caucasian 578 (82.0) 384 (81.2) 0.7273
Medical History
Non-ischemic CM 319 (45.3) 266 (56.2) 0.0002
NYHA Class III 184 (26.1) 117 (24.7) 0.5989
Baseline EF, % 26.54 (6.3) 23.39 (6.7) <0.0001
Pulmonary disease 110 (15.6) 85 (18.0) 0.2838
Never smoker 185 (26.2) 130 (27.5) 0.7367
Hyperlipidemia 403 (57.2) 242 (51.2) 0.0425
Hypertension 365 (51.8) 245 (51.8) 0.9936
Stroke 42 (5.96) 23 (4.86) 0.4198
Diabetes 192 (27.2) 124 (26.2) 0.6989
NSVT 146 (20.7) 90 (19.0) 0.4796
Syncope 57 (8.09) 30 (6.3) 0.2623
QRS duration <120 ms 326 (46.2) 161 (34.0) <0.0001
Atrial fibrillation by ECG 36 (5.11) 35 (7.4) 0.1050
Blood pressure - diastolic, mmHg 70.86 (10.7) 72.01 (11.6) 0.0806
Blood pressure - systolic, mmHg 119.3 (19.30) 122.0 (19.6) 0.0187
Pulse, beats/min 73.25 (13.9) 75.10 (14.4) 0.0272
Sodium, mg/dl 139.3 (3.1) 139.3 (3.0) 0.9226
Potassium, mEq/L 4.4 (0.5) 4.4 (0.4) 0.5401
Ace inhibitor 596 (84.5) 396 (83.7) 0.7058
Beta blocker 503 (71.4) 314 (66.4) 0.0701
Digoxin 490 (69.5) 312 (66.0) 0.2012
Diuretic (loop) 566 (80.3) 370 (78.2) 0.3911
Spironolactone 117 (16.6) 85 (18.0) 0.5395
Statins 307 (43.6) 180 (38.1) 0.0606
Months from CHF diagnosis 45.11 (50.1) 32.46 (42.3) <0.0001