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A formalized transition program in cystic fibrosis: a ten-year retrospective experience of 97 patients in Lyon.
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  • Gaelle Bourgeois,
  • Fanny Magne,
  • Stephane DURUPT,
  • Raphaele NOVE-JOSSERAND,
  • Philippe Reix,
  • Isabelle Durieu,
  • Quitterie Reynaud
Gaelle Bourgeois
Centre Hospitalier Lyon-Sud
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Fanny Magne
Centre Hospitalier Lyon-Sud
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Stephane DURUPT
Hospices Civils de Lyon, Centre Hospitalier Lyon Sud
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Raphaele NOVE-JOSSERAND
Hospices Civils de Lyon, Centre Hospitalier Lyon Sud
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Philippe Reix
hôpital debrousse
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Isabelle Durieu
Hospices Civils de Lyon. UCBL1
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Quitterie Reynaud
Centre Hospitalier Lyon-Sud
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Peer review status:UNDER REVIEW

10 Jul 2020Submitted to Pediatric Pulmonology
10 Jul 2020Assigned to Editor
10 Jul 2020Submission Checks Completed
11 Jul 2020Reviewer(s) Assigned

Abstract

Introduction: The prognosis of cystic fibrosis (CF) has dramatically changed over the past decade in France, mostly due to global improvements in specific care. Currently, the majority of French CF patients are adults, meaning they went through a transition process from a pediatric CF center to an adult CF center. To determine the impact of that transfer on clinical evolution, we report the transition procedure of our CF center in Lyon. Materials and Methods: From January 2006 to December 2016, 117 CF patients went through a standardized transition process from the pediatric to the adult CF center of Lyon. We compared the clinical evolution of the patients over 3 periods starting the year before transfer and ending the next year after transfer. Clinical data taken into account were FEV1%, BMI, pulmonary colonization, number of antibiotic courses, and number of days of hospitalization per year and outpatient visits per year. Results: No significant differences were observed between respiratory and nutritional status, pulmonary colonization, number of antibiotic courses, and numbers of hospitalizations and visits when comparing the 3 periods of observation (the year before, the year after and the next year after transfer) around transition. Conclusion: The standardized procedure of transition in Lyon is associated with the maintenance of a stable clinical status of our CF patients.