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\begin{document}

\title{Clinical Predictors and Trends of Pacer Insertion, Complications, and
Mortality Over the Recent Years Using a Large Database}



\author[1]{Mohammad Reza Movahed}%
\author[1]{Mehrtash Hashemzadeh}%
\author[2]{Nandini Sodhi}%
\affil[1]{The University of Arizona College of Medicine Phoenix}%
\affil[2]{The University of Arizona College of Medicine Tucson}%


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  \date{May 16, 2024}


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\begin{abstract}
Background: Pacemakers are an essential tool in managing
bradyarrhythmias. Using the large Nationwide Inpatient Sample (NIS)
database, we evaluated complications, trends and mortality rates of
pacemakers over 2016 2020. Methods: We utilized International
Classification of Diseases, Tenth Revision, Clinical Modification
(ICD-10-CM) coding for our study. We evaluated clinical predictors,
complications and mortality of pacemakers using the NIS database.
Results: Significant independent Clinical predicators for pacer
insertion are: NSTEMI: OR, 1.85; 95\% CI, 1.80--1.91; p\textless{}0.001,
hypertension: OR, 4.26; 95\% CI, 4.19--4.34; p\textless{}0.001,
hyperlipidemia: OR, 3.01; 95\% CI, 2.97--3.05; p\textless{}0.001, atrial
fibrillation/flutter: OR, 4.68 95\% CI, 4.62--4.74; p\textless{}0.001,
diabetes: OR, 1.49; 95\% CI, 1.47--1.51; p\textless{}0.001, chronic
kidney disease: OR, 1.99; 95\% CI, 1.97--2.02; p\textless{}0.001,
smoking: OR, 1.41; 95\% CI, 1.31--1.43; p\textless{}0.001, COPD: OR,
1.11; 95\% CI, 1.09--1.13; p\textless{}0.001, valvular heart disease:
OR, 5.31; 95\% CI, 5.21--5.41; p\textless{}0.001, systolic heart
failure: OR, 1.98; 95\% CI, 1.94--2.02; p\textless{}0.001, prior PCI:
OR, 2.30; 95\% CI, 2.26--2.34; p\textless{}0.001, obesity 1.19; 95\% CI,
1.17--1.22; p\textless{}0.001), history of CABG\{:OR, 2.48; 95\% CI,
2.43--2.52; p\textless{}0.001, STEMI: OR, 1.86; 95\% CI, 1.79--1.93;
p\textless{}0.001, history of cardiomyopathy: OR, 1.90; 95\% CI,
1.78--2.03; p\textless{}0.001, and endocarditis: OR, 1.77; 95\% CI,
1.53--2.04; p\textless{}0.001. Pacemaker complication rates is around
2\% Mortality around 1.44\% Conclusion: We found many predictors for the
need of pacemaker insertion. Mortality and complications have remained
low over recent years.%
\end{abstract}%



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\verb`No_titel_Movahed_Clinical_predictors_for_Pacer_nadalin.docx`  available at \url{https://authorea.com/users/339701/articles/687081-clinical-predictors-and-trends-of-pacer-insertion-complications-and-mortality-over-the-recent-years-using-a-large-database}

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