Number of concomitant medications in patients classified by clinical factors
The number of concomitant medications was significantly higher in patients with a higher CCI score (>=7 vs. <=6;P = 0.012), metastasis in multiple organs (>=2 vs. 0 or 1; P = 0.035), poorer PS (>=2 vs. 0 or 1;P =0.029), and a higher GRIm-Score (>=2 vs. 0 or 1;P = 0.016) (Figure 4A ). The cluster analysis dendrogram revealed that compared to other factors, CCI scores have a relatively close correlation with the number of concomitant medications(Figure 4B ).