RESULTS
The data from the PPMI trial are openly available upon request (https://www.ppmi-info.org/access-data-specimens/). The data used in this analysis were downloaded on 3 Jan 2020; 233607 item level observations from 423 de novo PD patients were used in the analysis. The SoS observations are shown in Figure 2 (upper left), and key baseline characteristics are summarized in Table 1.