References:

1. Stoll C, Dott B, Alembik Y, Roth MP. Associated congenital anomalies among cases with Down syndrome. Eur J Med Genet : sn, 2015 Dec;58(12):674-80.
2. Watts R, Vyas H. An overview of respiratory problems in children with Down’s syndrome. 2013 Oct, Arch Dis Child., pp. 98(10):812-7.
3. Bloemers BL, Broers CJ, Bont L, Weijerman ME, Gemke RJ, van Furth AM. Increased risk of respiratory tract infections in children with Down syndrome: the consequence of an altered immune system. Microbes Infect. 2010 Oct;12(11):799-808.
4. Ram G, Chinen J. Infections and immunodeficiency in Down syndrome. Clin Exp Immunol. 2011 Apr;164(1):9-16.
5. Alsubie HS, Rosen D. The evaluation and management of respiratory disease in children with Down syndrome (DS). Paediatr Respir Rev. 2017;26:49‐54.
6. Fitzgerald P, Leonard H, Pikora TJ, Bourke J, Hammond G.Hospital admissions in children with down syndrome: experience of a population-based cohort followed from birth. PLoS One. 2013 Aug 13;8(8):e70401
7. So SA, Urbano RC, Hodapp RM. Hospitalizations of infants and young children with Down syndrome: evidence from inpatient person-records from a statewide administrative database. J Intellect Disabil Res. 2007 Dec;51(Pt 12):1030-8.
8. De Lausnay M, Verhulst S, Boel L, Wojciechowski M, Boudewyns A, Van Hoorenbeeck K. The prevalence of lower airway anomalies in children with Down syndrome compared to controls. Pediatr Pulmonol. 2020 May;55(5):1259-1263.
9. Bertrand P, Navarro H, Caussade S, Holmgren N, Sánchez I.Airway anomalies in children with Down syndrome: endoscopic findings. Pediatr Pulmonol. 2003;36(2):137‐141.
10. Hamilton J, Yaneza MM, Clement WA, Kubba H. The prevalence of airway problems in children with Down’s syndrome. Int J Pediatr Otorhinolaryngol. 2016;81:1‐4.
11. J, Pravit. Bronchoscopic findings in Down syndrome children with respiratory problems. J Med Assoc Thai. 2014;97:S159‐S163.
12. Wu BG, Segal LN. Lung Microbiota and Its Impact on the Mucosal Immune Phenotype. Microbiol Spectr. 2017 Jun;5(3).
13. Marsh RL, Smith-Vaughan HC, Chen ACH, Marchant JM, Yerkovich ST, Gibson PG, Pizzutto SJ, Hodge S, Upham JW, Chang AB. Multiple Respiratory Microbiota Profiles Are Associated With Lower Airway Inflammation in Children With Protracted Bacterial Bronchitis.Chest. 2019 Jan 17. pii: S0012-3692(19)30010-8.
14. Ahmed B, Cox MJ, Cuthbertson L, James PL, Cookson WOC, Davies JC, Moffatt MF, Bush A. Comparison of the upper and lower airway microbiota in children with chronic lung diseases. PLoS One. 2018 Aug 2;13(8):e0201156.
15. Verhulst S, Boel L, Van Hoorenbeeck K. Protracted bacterial bronchitis: bronchial aspirate versus bronchoalveolar lavage findings: a single-centre retrospective study. BMJ Paediatr Open. 2019 Jun 20;3(1):e000507.
16. Cant AJ, Gibson PJ, West RJ. Bacterial tracheitis in Down’s syndrome. Arch Dis Child. 1987 Sep;62(9):962-3.
17. Orlicek SL, Walker MS, Kuhls TL. Severe mycoplasma pneumonia in young children with Down syndrome. Clin Pediatr (Phila). 1992 Jul;31(7):409-12.
18. Winters JL, O’Connor WN, Broughton RA, Noonan JA.Bordetella bronchiseptica pneumonia in a patient with Down syndrome: a case report and review. Pediatrics. 1992 Jun;89(6 Pt 2):1262-5.