SNV, single-nucleotide variant; Chr, chromosome; A1, minor allele; A2, major allele; MAF, minor allele frequency of A1 in all samples;OR (estimated for A1), odds ratio; CI, confidence interval; WES, whole-exome sequence; TS, Transcriptome sequencing;SULT1A2 , NC_000016.10; MAP3K21 , NC_000001.11. Adiposity was defined by fat mass percentage. Dyslipidemia was defined by TC, TG, LDL or HDL level abnormality.