Conclusion
This case report describes the challenging diagnosis of a non-secretor
plasmablastic plasma cell myeloma and highlights the importance of
remaining vigilant during morphological evaluation, regardless of the
initially suggested diagnosis. Furthermore, it stresses how essential it
is to integrate clinical, radiological and laboratory findings to obtain
all necessary information for a correct diagnosis, especially with
challenging and rare entities. Although there are no comprehensive
criteria to discriminate plasmablastic lymphoma from plasmablastic
non-secretor myeloma, distinction is important, as the treatment for
these two diseases is different.