3.2 Changes of serum MMP-9 concentration prior to and following treatment in different types of SSNHL.
Patients with SSNHL had a higher concentration of MMP-9 following treatment as compared with prior-treatment concentration, but it was not statistically significant (116.56±50.01ng/ml vs 131.45±45.33 ng/ml, p=0.054). Next, we compared the mean prior-treatment serum concentration of MMP-9 with post-treatment concentration in ascending, descending, horizontal, and profound group. (prior to treatment vs post-treatment, 99.76±23.44ng/ml vs 125.82±35.50ng/ml, 129.20±58.33ng/ml vs 148.91±66.43ng/ml, 112.42±66.59ng/ml vs 128.65±45.13ng/ml and 124.69±30.95ng/ml vs 129.20±43.01ng/ml, respectively) .An increase was found in all four groups, however, none of them had statistical significance (Fig.Ⅰ, P=0.094, P=0.574, P=0.191, P=0.867, respectively).