References
1. Toth NK, Csanadi Z, Hajas O, et al. Intracardiac Hemostasis and Fibrinolysis Parameters in Patients with Atrial Fibrillation. 2017;2017:3678017.
2. Cove CL, Albert CM, Andreotti F, Badimon L, Van Gelder IC, Hylek EM. Female sex as an independent risk factor for stroke in atrial fibrillation: possible mechanisms.Thrombosis and haemostasis. 2014;111(3):385-391.
3. Kirchhof P, Benussi S, Kotecha D, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Heart Journal.2016;37(38):2893-2962.
4. January CT, Wann LS, Calkins H, et al. 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons. Circulation.2019;140(2):e125-e151.
5. Litwinowicz R, Bartus M, Malec-Litwinowicz M, et al. Left Atrial Appendage Occlusion for Secondary Stroke Prevention in Patients with Atrial Fibrillation: Long-Term Results. Cerebrovascular Diseases. 2019:1-8.
6. Bajaj NS, Parashar A, Agarwal S, et al. Percutaneous left atrial appendage occlusion for stroke prophylaxis in nonvalvular atrial fibrillation: a systematic review and analysis of observational studies. JACC Cardiovascular interventions.2014;7(3):296-304.
7. Whitlock R, Healey J, Vincent J, et al. Rationale and design of the left atrial appendage occlusion study (LAAOS) III. Annals of cardiothoracic surgery. 2014;3(1):45.
8. Litwinowicz R, Bartus M, Burysz M, et al. Long term outcomes after left atrial appendage closure with the LARIAT device—Stroke risk reduction over five years follow-up.PloS one. 2018;13(12):e0208710.
9. Litwinowicz R, Bartus M, Ceranowicz P, et al. Left atrial appendage occlusion for stroke prevention in diabetes mellitus patients with atrial fibrillation: Long-term results.Journal of diabetes. 2019;11(1):75-82.
10. Litwinowicz R, Bartus M, Ceranowicz P, Kapelak B, Lakkireddy D, Bartus K. Stroke risk reduction after left atrial appendage occlusion in elderly patients with atrial fibrillation: longterm results. Polish archives of internal medicine. 2018;128(5):327-329.
11. Suwalski P, Witkowska A, Drobiński D, et al. Stand-alone totally thoracoscopic left atrial appendage exclusion using a novel clipping system in patients with high risk of stroke–initial experience and literature review.Kardiochirurgia i torakochirurgia polska= Polish journal of cardio-thoracic surgery. 2015;12(4):298.
12. Mills JD, Ariens RA, Mansfield MW, Grant PJ. Altered fibrin clot structure in the healthy relatives of patients with premature coronary artery disease. Circulation.2002;106(15):1938-1942.
13. Pieters M, Philippou H, Undas A, et al. An international study on the feasibility of a standardized combined plasma clot turbidity and lysis assay: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis.2018;16(5):1007-1012.
14. Hemker HC. Thrombin generation in a reconstituted system: a comment. Thrombosis and haemostasis.2002;87:551-554.
15. Kirchhof P, Benussi S, Kotecha D, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European heart journal.2016;37(38):2893-2962.
16. Blackshear JL, Odell JA. Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. The Annals of thoracic surgery.1996;61(2):755-759.
17. Di Biase L, Santangeli P, Anselmino M, et al. Does the left atrial appendage morphology correlate with the risk of stroke in patients with atrial fibrillation? Results from a multicenter study. Journal of the American College of Cardiology. 2012;60(6):531-538.
18. Mitusch R, Siemens HJ, Garbe M, Wagner T, Sheikhzadeh A, Diederich KW. Detection of a hypercoagulable state in nonvalvular atrial fibrillation and the effect of anticoagulant therapy. Thrombosis and haemostasis. 1996;75(2):219-223.
19. Califano F, Giovanniello T, Pantone P, et al. Clinical importance of thrombomodulin serum levels.European review for medical and pharmacological sciences.2000;4(3):59-66.
20. Zabczyk M, Majewski J, Lelakowski J. Thromboembolic events are associated with prolonged clot lysis time in patients with permanent atrial fibrillation. Polskie Archiwum Medycyny Wewnetrznej. 2011;121(11):400-407.
21. Adams TE, Huntington JA. Thrombin-cofactor interactions: structural insights into regulatory mechanisms. Arteriosclerosis, thrombosis, and vascular biology.2006;26(8):1738-1745.
22. Drabik L, Wolkow P, Undas A. Denser plasma clot formation and impaired fibrinolysis in paroxysmal and persistent atrial fibrillation while on sinus rhythm: association with thrombin generation, endothelial injury and platelet activation.Thrombosis research. 2015;136(2):408-414.
23. Roldan V, Marin F, Marco P, Martinez JG, Calatayud R, Sogorb F. Hypofibrinolysis in atrial fibrillation. American heart journal. 1998;136(6):956-960.
24. Camm AJ, Lip GY, De Caterina R, et al. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. European heart journal. 2012;33(21):2719-2747.
25. Litwinowicz R, Bartus M, Ceranowicz P, et al. Left atrial appendage occlusion for stroke prevention in diabetes mellitus patients with atrial fibrillation: Long-term results. Journal of diabetes. 2018.
26. Litwinowicz R, Bartus M, Ceranowicz P, Kapelak B, Lakkireddy D, Bartus K. Stroke risk reduction after LAA occlusion in elderly patients with atrial fibrillation: long-term results. Pol Arch Intern Med. 2018.
27. Wiebe J, Franke J, Lehn K, et al. Percutaneous Left Atrial Appendage Closure With the Watchman Device: Long-Term Results Up to 5 Years. JACC Cardiovascular interventions. 2015;8(15):1915-1921.
28. Bartus K, Morelli RL, Szczepanski W, Kapelak B, Sadowski J, Lee RJ. Anatomic analysis of the left atrial appendage after closure with the LARIAT device. Circulation Arrhythmia and electrophysiology. 2014;7(4):764-767.
29. Litwinowicz R, Bartus M, Kapelak B, et al. Reduction in risk of stroke and bleeding after left atrial appendage closure with LARIAT device in patients with increased risk of stroke and bleeding: Long term results. Catheterization and Cardiovascular Interventions. 2019.
30. Burysz M, Litwinowicz R, Bryndza M, Skowronek R, Ogorzeja W, Bartus K. Percutaneous left atrial appendage closure using the LAmbre device. First clinical results in Poland.Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2019;15(2):251-254.
Table 1. Patient characteristics