Definitions
Abnormal Liver function tests (LFT’s) were defined as an elevation of at least one of AST, ALT, ALP, GGT or bilirubin above the upper limit of normal reference range of local laboratory 7. The pattern of abnormal LFTs was defined as hepatocellular when patients presented with predominantly raised ALT and AST; cholestatic when patients showed predominantly raised ALP and GGT, and mixed when the extent of AST/ALT and ALP/GGT was similar 8. COVID-19 severity of each patient was based on the most severe condition during the entire course of the disease, with the clinical classification based on the most recently adopted tentative 8th edition protocol for diagnosis and treatment for COVID-19 patients, released by the national health commission of China 9. The primary outcome measure was defined as the composite endpoint of death or requirement for mechanical ventilation during hospitalization.