Peanut Oral food challenge (OFC)
An OFC was offered to any participant who had:
- SPT > 0 mm to peanut;
- Previous history of peanut allergy and SPT≥5mm;
- Previous history of peanut allergy whose testing suggested they might
have outgrown it (i.e. SPT < 5 mm or negative SPT)
- Participants who were infrequent consumers of peanut (i.e. who
consumed less than 3 grams of peanut protein at least 3 times in the
last 6 months).
All OFCs were open challenges unless there was investigator concern
about subjective symptoms, in which case a double blinded
placebo-controlled food challenge was performed. The open challenges
involved a single-dose cumulative challenge or 6-7 dose incremental
challenge if deemed to be high risk.