Peanut extract SPT mm
3 months**
12 months
36 months
7-11 year
|
0 (0, 0) (n=5)
4.5 (3, 7.5) (n=18)
8.5 (6.3, 10.3)
9.3 (7.3, 10.3)
|
0 (0, 2) (n=11)
1 (0, 4.8)
1.5 (0, 5)
0 (0, 2)
|
0.20
0.02
<0.001
<0.001
|
Peanut sIgE kUA/L
3 months
12 months
36 months
7-11 years
|
0.05 (0.03, 0.2) (n=18)
1.4 (0.64, 6.5) (n=16)
9.3 (1.6, 46.7) (n=19)
24.8 (3.6, 85.2)
|
0.06 (0.03, 0.2) (n=25)
1.5 (1.1, 5.4) (n=27)
0.8 (0.2, 1.5)
0.9 (0.1, 5.2) (n=27)
|
0.8
0.7
<0.001
<0.001
|
Peanut components-sIgE kUA/L
(3 months)
Ara h 1
Ara h 2
Ara h 3
Ara h 8
|
(n=18)
0.07 (0, 0.4)
0.01 (0.01, 2.0)
0.02 (0.002, 0.04)
0.003 (0.002, 0.005)
|
(n=25)
0.1 (0, 0.2)
0.005 (0.002, 0.01)
0.01 (0.005, 0.02)
0.003 (0.001, 0.005)
|
1.00
0.11
0.67
0.73
|
Peanut components-sIgE kUA/L (12 months)
Ara h 1
Ara h 2
Ara h 3
Ara h 8
|
(n=16)
0.4 (0.05, 4.0)
0.6 (0.07, 6.7)
0.06 (0.02, 0.3)
1.5 (0.03, 10.3)
|
(n=27)
0.2 (0.02, 0.7)
0.2 (0.02, 1.2)
0.1 (0.03, 0.5)
0.004 (0.001, 0.013)
|
0.81
0.39
0.49
0.24
|
Peanut components-sIgE kUA/L (36 months)
Ara h 1
Ara h 2
Ara h 3
Ara h 8
|
(n=19)
0.1 (0.04, 1.8)
4.0 (1.3, 28.3)
0.03 (0.02, 0.4)
1.5 (0.03, 10.3)
|
0.1 (0.03, 0.2)
0.04 (0.02, 0.2)
0.1 (0.06, 0.2)
0.04 (0.01, 0.5)
|
0.38
<0.001
0.72
0.14
|
Peanut components-sIgE kUA/L
(7-11 years)
Ara h 1
Ara h 2
Ara h 3
Ara h 6
Ara h 8
|
1.8 (0.12, 28.4)
16.3 (1.9, 54.5)
0.28 (0.02, 3.5)
10.4 (1.6, 31.9)
1.5 (0.03, 10.3)
|
(n=27)
0.06 (0.01, 0.2)
0.06 (0.03, 0.2)
0.06 (0.03, 0.2)
0.06 (0.03, 0.1)
0.26 (0.06, 0.6)
|
<0.001
<0.001
<0.01
<0.001
0.14
|
Peanut sIgG4 g/L
3 months
12 months
36 months
7-11 years
|
11.3 (0, 40.1) (n=17)
202.8 (74.6, 433.6) (n=16)
407.4 (175.7,1526.3) (n=18)
736.2 (210.9,1482.4)
|
7.3 (0, 27.3) (n=22)
78.3 (34.2, 506.9) (n=26)
353.4 (96.4, 1882.8)
523.7 (124.5,2673.3) (n=27)
|
0.54
0.69
0.51
0.88
|
Peanut sIgG4:sIgE ratios
3 months
12 months
36 months
7-11years
|
9.2 (0, 211.1) (n=17)
35.9 (7.1, 166.8) (n=16)
19 (8.6, 51.2) (n=12)
11.3 (5.1, 35.1)
|
15 (0, 326.2) (n=22)
15.1 (4.7, 296.4) (n=26)
191.4 (39.6, 2493.6) (n=19)
544 (30.4, 2448) (n=27)
|
0.95
0.70
<0.01
<0.001
|
MAT to peanut (%CD63 LAD2 cells)
3 months
12 months
36 months
7-11 years
|
10.7% (8.7-12.7) (n=2)
0.7% (-0.34, 11.6) (n=15)
11.5% (1.3, 30.2)
12.2% (5.0, 35.8)
|
–
0.32% (-0.1, 7.8) (n=25)
0.19% (-0.2, 0.6) (n=26)
0.3% (0.1, 0.8) (n=27)
|
–
0.31
p<0.001
p<0.001
|
*The number of patients in the groups differ based on sample
availability and are denoted separately.
**At the 3m time point, only children in the early introduction group
had SPT performed and very few had sufficient bloods for MAT to be
performed.
|
*The number of patients in the groups differ based on sample
availability and are denoted separately.
**At the 3m time point, only children in the early introduction group
had SPT performed and very few had sufficient bloods for MAT to be
performed.
|
*The number of patients in the groups differ based on sample
availability and are denoted separately.
**At the 3m time point, only children in the early introduction group
had SPT performed and very few had sufficient bloods for MAT to be
performed.
|
*The number of patients in the groups differ based on sample
availability and are denoted separately.
**At the 3m time point, only children in the early introduction group
had SPT performed and very few had sufficient bloods for MAT to be
performed.
|