Serdar Aydın

and 4 more

Objective: Intra-abdominal pressure (IAP) was defined as the steady state pressure concealed within the abdominal cavity. Sustained increased in IAP has become the focus of attention in many disciplines which is has impact on pulmonary, cardiovascular systems. Pelvic organ prolapse might be the consequences of compensation of abdominal compliance to increased IAP. The aim of this study was to evaluate the effect of laparoscopic sacrocolpopexy in patients with severe uterovaginal prolapse on intraabdominal presurre. Design: Prospective, case control study Setting: Tertiary Urogynecology Unit Population: Women with advanced symptomatic stage ≥3 uterovaginal prolapse. Method: IAPs were measured in 13 women, before and 6 month after laparoscopic sacrocolpopexy and in 13 controls. Main Outcome Measure: Preoperative and postoperative IAP. Results: The mean preoperative IAP of controls (4.5 ± 1 mmHg) was not significantly different than to women with stage ≥3 uterovaginal prolapse (p=0.1). The mean postoperative IAP at 6 months control was 8.6 ±2.5 mmHg and significantly higher than postprocedure IAP of control group (4.8 ± 1.1 mmHg) (p<0.0001). IAP of prolapse group was significantly correlated with gravidy (r = 0.65, P < 0.01) and parity (r = 0.87, P < 0.001). Conclusions: IAP significantly increases after pelvic reconstructive surgery in our pilot study. The association of increased IAP with pelvic organ prolapse and its clinical consequences should be evaluated with large, well designed, with studies