Design
160 patients who diagnosed otomycosis from out-patient department were selected as subjects, they were divided into traditional group (TG) and improved group (IG) by random number table method equally.The treatment was implemented once every other day for three times in total in two groups. At 3d, 1wk, 1mo, 6mo of treatment, cure rates were analyzed and compared between the two groups,at 6mo of treatment the recurrence rate was compared between the two groups.At the follow-up time points, if cure criteria were met, use only the drug.Safety was evaluated by recording any adverse events.
Traditional method : soaked the EAC with 3% hydrogen peroxide for a few minutes. Under the otoendoscopy, the mildew moss, attachment or secretions were removed by the cerumen hook and attractor. Then covered the surface of EAC and tympanic membrane with pevisone by a cotton swab(Figure1 A)
Improved method : specially processed cotton balls were used compared to the traditional method. After the soaking and cleaning step, the cotton batting of a cotton swab was taken down and shaped into two small cotton balls, inserted the tail end of the cotton swab into one cotton ball and pushed it till reached the tympanic membrane surface and then rotated it, the lesions attached to the surface of EAC which could not be cleaned by the cerumen hook and attractor could be all wiped down by the cotton ball, the remaining hydrogen peroxide could also be absorbed away. Then sent the second cotton ball which fully mixed with pevisone to the tympanic membrane like before, rotated it outward until the surface of EAC was covered with pevisone uniformly, when the cotton ball tightly wrapped around the tail of the cotton swab after rotation, they could be extracted out together. (Figure1 B、C、D、E)