Discussion
Thyroid storm may be caused by various stresses, such as infection,
trauma, and surgery in a patient with untreated or poorly controlled
underlying thyroid disease, resulting in an overproduction of thyroid
hormones that can lead to multiple organ malfunctions. In Japan, the
annual incidence of thyroid storm is 0.2per 100,000, and the mortality
rate of patients from thyroid storm is approximately 11%[1]. Thus,
thyroid storm is a rare but life-threatening condition requiring urgent
treatment.
In general, thyroid storm is diagnosed according to the Burch-Wartofsky
criteria[2]. Retrospectively, it was obvious that our patient had
all the telltale signs, and we calculated the patient’s score to be
105(a score greater than 60 is consistent with thyroid storm).
Therefore, it would have been easy to make a diagnosis of thyroid storm
had we been more aware of the condition. Unfortunately, it was not until
we performed a tracheotomy that we were led to suspect hyperthyroidism
due to the abnormal development of blood vessels around the thyroid.
Since we did not have previous knowledge or experience of a thyroid
storm, we were trying to deal with each symptom individually until the
correct diagnosis.
The differential diagnosis of thyroid storm includes cardiogenic shock,
malignant hyperthermia, and sepsis. In this case, we had performed
mitral repair on the patient due to reduced cardiac function. Therefore,
we initially assumed that the respiratory failure and tachycardia were
caused by severe heart failure. In addition, our patient had Becker
muscular dystrophy as a co-morbidity, which has known to be a risk
factor for malignant hyperthermia related to general anesthesia[3].
This condition also made the diagnosis difficult.
There have only been a few case reports of thyrotoxicosis and thyroid
storm in the peri-operative period of open-heart surgery, all of which
occurred in coronary artery bypass grafting and were associated with
coronary artery spasm and increased myocardial oxygen demand[4-8].
To the best of our knowledge, this is the first case report of thyroid
storm occurring after cardiac valve surgery.
Patient consent statement. This patient signed informed consent
to participate in our study.
Availability of data. All the co-authors have full access to
the patient data. Also, the datasets during and/or analyzed during the
current study available from the corresponding author on reasonable
request.
Conflicts of interest . The authors declare that they have no
competing interests.
Funding. None
Authors’ contributions . All authors contributed to the writing
of the final manuscript.