Introduction
Cryoglobulinemia is a clinical disorder characterized by the presence of
cryogobulins (CGs) in the serum. CGs are immunoglobulins (IGs) that
precipitate in vitro at temperatures below the normal body temperature
(<37°C) and redissolve upon warming. Cardiovascular surgeries,
such as cardiopulmonary bypass (CPB) usually requires systemic
hypothermia, has a risk of organ disorders due to microangiopathy
induced a rapid increase in blood viscosity. We present a case of
ascending aorta replacement with CPB under deep hypothermic circulatory
arrest in a patient who experienced acute aortic dissection during
cryoglobulinemia treatment.