Measurement of whole blood hsCRP,MPV and basophil
HsCRP concentrations were measured by a immune scattering Nepholometry method using DELTA specific protein immunoanalyzer(Japan).Basophil count and MPV concentrations were measured by Sysmex XN-3000 Hematoiogy System(Japan).All assays were performed according to manufacturer’s detailed instructions.
Statistics
The data in this study were presented as mean ± standard deviation. Statistical analysis of differences between the two groups was determined by the Unpaired t test. The correlations were assessed by the Spearman’s rank test.P<0.05 was considered to demonstrate statistical differences. The statistical analysis was performed by graphpad prism (GraphPad Software, San Diego, CA, USA).
Results
Levels of Whole blood hsCRP ,basophil count and MPV in patients with CSU
Concentrations of hsCRP ,basophil count and MPV in patients with CSU were within their normal ranges. The CSU patients showed significantly higher concentrations of hsCRP and MPV than the controls(p<0.0001;Fig 1 and Table 1). But patients with CSU displayed significantly lower levels of basophil count than the controls(p=0.0024;Fig 1 and Table 1).
Relationship of clinical disease severity towhole blood