Measurement of whole blood hsCRP,MPV and basophil
HsCRP concentrations were measured by a immune scattering Nepholometry
method using DELTA specific protein immunoanalyzer(Japan).Basophil count
and MPV concentrations were measured by Sysmex XN-3000 Hematoiogy
System(Japan).All assays were performed according to manufacturer’s
detailed instructions.
Statistics
The data in this study were presented as
mean ± standard deviation.
Statistical analysis of
differences between the two groups was determined by the Unpaired t
test. The correlations were assessed by the Spearman’s rank
test.P<0.05 was considered to demonstrate statistical
differences. The statistical analysis was performed by graphpad prism
(GraphPad Software, San Diego, CA, USA).
Results
Levels
of Whole blood hsCRP
,basophil count and MPV in patients with CSU
Concentrations of hsCRP ,basophil
count and MPV in patients with CSU were within their normal ranges. The
CSU patients showed significantly higher concentrations of hsCRP and MPV
than the
controls(p<0.0001;Fig
1 and Table 1). But patients with CSU displayed significantly lower
levels of basophil count than the controls(p=0.0024;Fig 1 and Table 1).
Relationship
of clinical disease
severity towhole
blood