Conclusion
Because little is known about the clinical course and progression of SARS-CoV-2 infection in newborns after cardiac surgery, the duration of ECMO support, cannulation and anticoagulation strategy, and the recovery timetable to guide treatment is unclear. Our case emphasizes the clinical course of this disease leading to mortality, as well as the difficulties in managing ARDS and ECMO in the context of SARS-CoV-2 syndrome, especially in newborns who underwent cardiac surgery.