Results
Forty pregnant women with COVID-19 were included in the study. The demographic information of the patients are shown in Table 1. Two patients had a history of chronic disease (Type 2 Diabetes Mellitus and Hypothyroidism).
Most of the patients presented with cough complaints (50%). The most common symptoms accompanied by cough were fever and shortness of breath. A significant number of patients were asymptomatic (42.5%). While 15 patients needed nasal oxygen support during their hospitalization, 2 of our patients were hospitalized in the intensive care unit (ICU) due to serious respiratory problems. We divided the patients into groups according to stages of CT findings. We detected 10 patients with mild involvement, 11 patients with moderate involvement and 8 patients with severe involvement. Lung CT finding and the clinical features of the patients are summarized in Table 2.
Laboratory findings of the pregnant at admission such as complete blood count, coagulation tests, liver function tests, ferritin and CRP were examined (Table 3).
Thirty-four of the patients had a c-section and six of them had a vaginal delivery. A patient with a previous c-section had severe AST (1560 U / L) and ALT (435 U / L) levels. Oxygen saturation under oxygen support was 94%. She had tachycardia (130 beats per minute) and shortness of breath. When she was 36 weeks of pregnancy, the decision was made by cesarean delivery. Four babies needed neonatal intensive care unit (NICU). Obstetric and neonatal characteristics are demonstrated in Table 4.
Forty-five percent of the patients received only hydroxychloroquine treatment. One patient was followed up without treatment. Low molecular weight heparin treatment (LMWH) was started for all patients. Patients with a D-dimer value above 2 mg / L were administered LMWH twice daily. Treatment options are shown in Table 5.