Conclusion
The results of this scoping review highlight that nonadherence to the
medication among patients with MDD is a major obstacle in reducing
public health challenges in both developed and developing countries. The
evidence shows that patients with MDD have a high rate of medication
nonadherence. However, accurate assessments of medication adherence will
provide better evidence on the outcomes, risk factors, and interventions
to improve medication adherence. Numerous measurements available for
assessments of medication adherence, also need to prove to be valid,
reliable, and sensitive. However, the selection of
measurements should be based on
researcher or healthcare professionals’ attributes, goals, resources of
the clinical setting, or study. Although, none of the measurements can
be considered as a gold standard, and the triangulation of measures is
recommended. The behaviors of taking mediation are often faced
multi-factorial causes, identify of it important to implement
appropriate medication adherence enhancing interventions. Also,
interventions require several components to focus on these factors, and
health care professionals must follow a systematic process to assess
possible factors.