Sirey et al. (2017)19
|
3 years |
The 5-fold increase
in adherence during the first 6 weeks of care |
BMQ |
Self-Report |
Alekhya et al. (2015)21
|
6 months |
30.1% |
DAI |
Self-Report |
Abegaz et al. (2017)22
|
4 months |
10.6% |
MMAS
(8-items) |
Self-Report |
Al-Jumah et al. (2014)23
|
5 months |
47.1% |
MMAS
(8-items) |
Self-Report |
Yau et al. (2014)25
|
1 year |
54% |
The prescription
record and also the electronic and written medical records
(filled prescriptions for any
antidepressants with no gaps of >15 days within 6 months
after initiation of treatment) |
Claims Database |
Mert et al. (2015)34
|
1 year |
69.2% |
Not taking
any medicine for at least 1 week during the 6-month term before the
study was regarded as medication nonadherence; from first-degree
relatives and patient files. |
Self-Report and patient
record |
Al-Jumah et al. (2014)46
|
5 months |
47.1% |
MMAS
(8-items) |
Self-Report |
Aljumah and Hassali (2015)47
|
6 months |
NM |
MMAS
(8-items) |
Self-Report |
Baeza-Velasco et al. (2019)48
|
NM |
29.7% |
MARS |
Self-Report |
Bhat et al. (2018)49
|
5 months |
81% |
Unstructured
scale contains one question |
Self-Report |
Burnett-Zeigler et al. (2014)50
|
4 months |
NM |
BMQ |
Self-Report |
Chatterjee et al. (2017)51
|
NM |
NM |
MMAS (8-items) |
Self-Report |
De las Cuevas et al. (2014)52
|
8 months |
53.8% |
MGLS (4-items) |
Self-Report |
De Las Cuevas et al. (2014)53
|
4 months |
49.6% |
MGLS (4-items) |
Self-Report |
Isa et al. (2018)54
|
2 months |
NM |
Attitude to
Medication Adherence Questionnaire |
Self-Report |
Klein et al. (2017)55
|
NM |
51.9% |
MGLS (4-items) |
Self-Report |
Lu et al. (2016)56
|
9 months |
37.8% |
MGLS
(4-items) |
Self-Report |
Lucca et al. (2015)57
|
1 year |
58.2% |
MARS |
Self-Report |
Novick et al. (2015)58
|
7 months
|
Patient-reported: 42.5%;
clinician-reported: 85.4%
|
-Clinicians were asked to provide their opinion on whether the patient
had been adherent with the prescribed medication(s) for MDD since the
baseline visit.
-Patients were asked how regularly they took the medications prescribed
for MDD since the baseline visit.
|
Self-Report
|
Serrano et al. (2014)59
|
6 months |
72.4% |
SMAQ |
Self-Report |
Shrestha Manandhar et al. (2017)60
|
4 months |
37% |
Structured questionnaire |
Self-Report |
Taleban et al. (2016)61
|
NM |
NM |
MARS |
Self-Report |
Vannachavee et al. (2016)62
|
3 months |
I:
41.17±2.87; C: 22.58±17.07 |
SMIR |
Self-Report |
Bushnell et al. (2016)63
|
6 months |
45% |
Non-persistent if treatment had been stopped before 180 days after the
index antidepressant’s dispensing date |
Medical and pharmaceutical
Claims Database |
Green et al. (2017)64
|
NM |
54% |
Medical Record |
Claims Database |
Grover et al. (2018)65
|
1 year
|
3 months (34.3%)
3‑6 months (25%)
6‑12 months (10%)
|
Medical record
|
Claims Database
|
Holvast et al. (2019)66
|
2 years
|
Initiation: 86.5%
Optimal implementation: 84.8%
Persistence: 62.9%
|
Three measures of non-adherence (Non-initiation (not dispensed by the
SFK database within 14 days), suboptimal implementation (MPR),
Non-persistence (discontinuation within 294 days after first
dispense))
|
Claims Database
electronic medical records
|
Klang et al. (2015)67
|
24 weeks |
I:55%; C:15.2% |
The prescription fill method to
assess adherence (the proportion of compliance during the first 24
weeks) |
Claims Database |
LeBlanc et al. (2015)68
|
2 years |
I:67.7%; C:65.5% |
PDC |
Claims Database |
Slabbert et al. (2015)69
|
6 years |
34% |
MPR |
Claims Database |
Zhang et al. (2016)70
|
1 year |
17.8% |
The duration of time from
initiation to discontinuation of therapy. |
Claims
Database |
Hammonds et al. (2015)71
|
2 years and 7 months |
45% |
Percent adherence was calculated
by dividing the actual number of pills taken by the expected number of
pills taken during the study period and multiplying the total by 100 |
Pill Count |
Pradeep et al. (2014)72
|
3 years |
I:11.1 ± 10.4;
C:3.33 ± 3.79 |
The total number
of weeks the subjects took antidepressant medication, pill counts to
ensure that patients took medication as prescribed by doctor. |
Pill
count |