rph=phenotypic correlation, rph-a=part of phenotypic correlation which is attributable to additive genetic effect, rph-e=part of phenotypic correlation which is attributable to unique environmental effect, IgE level=continuous value of allergen-specific IgE level, NA=not applicable. bold=statistically significantly different from 0.
Figure 1. Cholesky AE model. Path diagram of association within one individual. Capital A and E refer to latent factors, lower-case a and e refer to path coefficients onto the observed variables. Observed variables are depicted with a square. IgE level=continuous value of allergen-specific IgE level. Note: Variances of latent factors not depicted, but assumed fixed at 1.
Figure 2. Explained correlation between asthma and FENO, re-weighted by sampling probability and adjusted for ICS-use. The height of the bar represents the phenotypic correlation, rph. A = Additive genetic effects, E = unique environmental effects. The color coding represents additive genetic effects, rph-a, or unique environmental effects, rph-e, on the total rph, IgE level=continuous value of allergen-specific IgE level.