Remdesivir |
Remdesivir |
|
Inhibits Viral Synthesis |
Stopping genome replication by blocking the
polymerase activity |
6-12 vials to be administered for a Patient with
severe attack |
Infusion related reaction (including hypotension,
nausea, vomiting, diaphoresis, and shivering) |
1000 Trials in Punjab
started on 09-june-2020 |
(Services, 2020) |
Clexan |
Enoxaprin |
|
Anticoagulant |
Accelerate the activity of antithrombin III,
inhibition of coagulation factors |
40mg once a Day in start of
Covid-19, In severe attack 12 hourly |
Unusual bleeding, or any bleeding
that will not stop, purple or red spots under your skin. |
|
|
Xarelto |
Rivaroxaban |
|
Anticoagulant |
Inhibit free and clot bound factor Xa |
10mg once a
day |
Increases the risk of thrombotic events |
|
|
Depo-Medrol |
Methyl-predinisolone |
|
Corticosteroid |
Decrease the inflammatory cycle |
0-1mg/kg/day for 5
consecutive days. |
Black, Tarry Stools, Joint Pain, Limp, Blurred
Vision, Joint Pain, Blindness. |
|
(C. Wu et al., 2020) |
Stromectol |
Ivermectin |
|
Anti-parasite |
Inhibits the replication of SARS-CoV-2 |
600 ug/kg
dose daily for 3 days |
Fever, pruritus, and skin rashes. |
Trials are
done on Patients with mild to moderate attack of Covid-19. |
(Caly et
al., 2020) |
Azasite/ Z-max |
Azithromycin + Chloroquine |
|
Antibiotic/ additional immunodulatory effects |
Binds to the 23s of
rRNA of the bacterial 50s Ribosomal unit. Stop Sbacterial protein
synthesis |
2 Tabs Hydoxychloroquine twice a day and 2 Tabs Azithromycin
twice a Day. |
Diarrhea, loose stools, and nausea. |
9 Patients were
kept under trial, 4 in PKLI and 5 in other hospitals. |
(Yousufzai,
2020) |
Acterma |
Tocilizumab |
C6428H9976N1720O2018S42
|
Interleukin-6 inhibitor |
Inhibits T-cells differentiation binds with
membrane bound IL-6 receptors. |
80 mg/4ml, 200 mg/10 ml for intravenous
injection |
Sinus pain, mild stomach cramps, urinary tract infection |
|
(Malik, 2020) |