Figure Legends
FIGURE 1. Flow Diagram of Patient Inclusion
FIGURE 2. Trajectory of percent predicted lung function
outcomes over time pre and post-treatment by sex (a) Trajectory of
Forced Expiratory Volume in 1 Second (FEV1) (b) Trajectory of Diffusion
Capacity of the Lungs for Carbon Monoxide Adjusted for Hemoglobin
(DLCOadj) (c) Trajectory of Total Lung Capacity (TLC).
Each point represents the average pulmonary function of one or more
individual patients during that one-month time period. FEV1 was
available for n=86 (100%), DLCOadj for n=78 (91%), and TLC for n=86
(100%). The y-axis dotted line represents the lower limit of normal for
lung function in children. The x-axis dotted line represents the date of
treatment completion, or time zero. The blue line represents the
trajectory for the overall population.
E-IMAGE 1. Trajectory of percent predicted Forced Expiratory
Volume in 1 Second pre and post-treatment in a subset of patients (n=65)
receiving both bleomycin and radiation therapy. FEV1,Forced Expiratory Volume. The y-axis dotted line represents the lower
limit of normal for lung function in children. The x-axis dotted line
represents the date of treatment completion, or time zero. The blue line
represents the trajectory for the overall population.