Methods
In this single-center, retrospective cohort study, we included pediatric cancer patients diagnosed at <18 years old between January 1994 and December 2014. Patients were included if they received pulmonary toxic exposure: either chemotherapy (bleomycin, busulfan, lomustine carmustine or cyclophosphamide) or thoracic radiation. Outcomes included percent predicted values for spirometry, lung volumes, and diffusion capacity of the lungs post-treatment.