Figure Legends
FIGURE 1. Flow Diagram of Patient Inclusion
FIGURE 2. Trajectory of percent predicted lung function outcomes over time pre and post-treatment by sex (a) Trajectory of Forced Expiratory Volume in 1 Second (FEV1) (b) Trajectory of Diffusion Capacity of the Lungs for Carbon Monoxide Adjusted for Hemoglobin (DLCOadj) (c) Trajectory of Total Lung Capacity (TLC).
Each point represents the average pulmonary function of one or more individual patients during that one-month time period. FEV1 was available for n=86 (100%), DLCOadj for n=78 (91%), and TLC for n=86 (100%). The y-axis dotted line represents the lower limit of normal for lung function in children. The x-axis dotted line represents the date of treatment completion, or time zero. The blue line represents the trajectory for the overall population.
E-IMAGE 1. Trajectory of percent predicted Forced Expiratory Volume in 1 Second pre and post-treatment in a subset of patients (n=65) receiving both bleomycin and radiation therapy. FEV1,Forced Expiratory Volume. The y-axis dotted line represents the lower limit of normal for lung function in children. The x-axis dotted line represents the date of treatment completion, or time zero. The blue line represents the trajectory for the overall population.