Clinical applicability of the study
With the development and improvement of minimal invasive therapy for
early esophageal neoplasms, it has become more important to define
high-risk groups and to perform UGI screening to detect early
ESCNs.31 In our study, those patients underwent
routine IEE screen without symptoms at the time of examination had more
early Tis lesions (44% vs. 0%, p =0.0359) and more received
minimal invasive therapy (75% vs. 0%, p =0.0013) than those with
symptoms at examination. Although we did not make the survey of quality
of life in patients with ESCNs after treatment, according to the
literature’s report, patients underwent minimal invasive therapy did
have the good quality of life. 18,32
In addition to the diagnosis of the malignant neoplasms of the
esophagus, 46 patients (46%) had found the non-malignant problems. The
laryngopharyngeal reflux was the most common (42%) problems at the IEE
examination. It may have some benefits to treat the non-malignant
diseases.